East Bay AWIS Event Summary

Apr 302012
 

ebAWIS May Chapter Meeting – May 24th at Novartis, 6:30 to 8:30 pm
Understanding and Controlling RNA-protein Complexes Involved in Myotonic Dystrophy Type 1

Presented by Professor Anne Baranger, Ph.D.
Director of Undergraduate Chemistry,
Faculty Assistant for Teaching and Learning, &
Adjunct Professor of Chemistry

 

On The Horizon

Launch Your Summer with the ebAWIS Social at Pyramid: June 12th, 6:00 – 8:00 pm


July Chapter Meeting at Novartis: July 26th, 2012 6:30-8:30 pm –

Join us for our Summer Science Event

Poh Teng will share some tips on Yoga for Lab Rats

Then enjoy a presentation by Charlotte Smith, PhD, on Water Safety:
Survival of Pathogenic E. coli after Ingestion by Tetrahymena


 Uncategorized

May Chapter Meeting at Novartis

Apr 302012
 

Understanding and Controlling RNA-protein Complexes Involved in Myotonic Dystrophy Type 1

Professor Anne Baranger, PhD
Director of Undergraduate Chemistry,
Faculty Assistant for Teaching and Learning, &
Adjunct Professor of Chemistry

Thursday, May 24, 2012, 6:30-8:30 pm

Myotonic dystrophy is the most prevalent form of muscular dystrophy and its two forms (DM1 and DM2) affect approximately 1 in 8000 people. These diseases cannot be cured, and there are no treatment options that delay disease progression. Both diseases are caused by large expansions of repeated sequences of DNA, which is transcribed into long repeated sequences of RNA. These RNAs are toxic, as a number of cellular proteins associate with them and as a result, these proteins are not available to perform their normal functions. Chief among these proteins is muscleblind-like protein (MBNL).  In healthy cells, MBNL controls the correct expression of proteins that are important for a number of processes including relaxing muscles after contraction and insulin regulation. We have investigated the binding specificity, thermodynamics, and kinetics of the MBNL1 protein for toxic repeat RNA sequences and normal RNA target sites. We have also identified small molecules that will associate with the toxic repeat RNA and release MBNL.                                                                                

Anne Baranger received a B.S. in Chemistry from the Massachusetts Institute of Technology, a Ph.D. in Chemistry from the University of California, Berkeley, and was a postdoctoral fellow at Yale University. She joined the Wesleyan University chemistry faculty in 1996, the University of Illinois chemistry faculty in 2006, and the University of California, Berkeley chemistry faculty in 2011. At the University of Illinois, she was Associate Head of the Department, Director of Graduate Studies, and was a Chancellor’s Fellow in the I-STEM Education Initiative. At UC Berkeley, she is Director of Undergraduate Chemistry and a Faculty Assistant for Teaching and Learning.

Thursday, May 24, 2012, 6:30-8:30 pm

Light supper* and networking 6:30pm – 7:00pm

NOTE: Registering w/ Eventbrite will say FREE, however fee will be collected at the door

$5 / members, $10 / non-members

Register at:  http://ebawismaychapter2012.eventbrite.com

Location: Novartis  5400 Hollis St, Building X-310 Emeryville, CA

Park in front of building – Directions here

Non Scientists and Men Welcome

 Chapter Meetings  Tagged with: , , , , , ,

eBAWIS Chapter Meeting at Novartis

Mar 122012
 

****Thank you to E & K Scientific for In-kind Support of this Event****

East Bay AWIS March Chapter Meeting – March 22, 6:30-8:30 pm

Inhibition of tumor invasiveness and metastasis by combined c-Met and VEGF blockade

Barbara Sennino, PhD   
UCSF

Most angiogenesis inhibitors used in the treatment of cancer block the actions of VEGF, a cytokine that promotes blood vessel growth and survival.  Treatment with the monoclonal anti-VEGF antibody bevacizumab, usually administered in combination with chemotherapy, delays progression and prolongs survival of some patients, yet many tumors eventually progress. Preclinical studies have shown that inhibition of VEGF signaling promotes invasiveness and metastasis in some tumor models. The mechanism underlying this form of resistance is not fully understood, but vascular pruning, intratumoral hypoxia, and increased expression of c-Met, the tyrosine kinase receptor for hepatocyte growth factor (HGF), could be contributing factors. We asked whether selective VEGF inhibition is sufficient to increase invasion and metastasis and whether selective c-Met inhibition is sufficient to block this effect. We found that hypoxia, HIF-1alpha, and c-Met mRNA, protein, and phosphorylation were increased in spontaneous pancreatic neuroendocrine tumors treated with a function-blocking anti-VEGF antibody.  Importantly, invasion and metastasis accompanying anti-VEGF therapy were blocked by administration of c-Met inhibitors. These results show that selective inactivation of VEGF reduces tumor growth but can lead to greater invasiveness and metastasis in mice.  However, inhibition of VEGF and c-Met together not only slows tumor growth but also decreases tumor invasiveness and liver metastasis and prolongs host survival.

Dr. Barbara Sennino is a cancer and vascular biologist. She earned her PhD in Italy and then joined the laboratory of Dr. Donald McDonald at UCSF. Her research has been focused on tumor angiogenesis and the cell-to-cell signaling and growth factor crosstalk between blood vessels and tumor cells. Over the past few years her interest has been centered on elucidating mechanisms by which tumor cells become invasive and metastasize to other organs and how these processes are affected by anti-angiogenic therapy. In collaboration with academic groups and pharmaceutical companies, she is currently studying the mechanisms underlying tumor regression and therapeutic resistance with the goal of guiding the development of novel therapeutic targets that can prevent and stop tumor cell aggressiveness and dissemination.

When:  March 22, 2012  6:30-8:30 pm

Light supper provided

Where:  Novartis,  5400 Hollis St, Building X-310 Emeryville, CA

Directions ,  Free Parking in front of building

Register  at http://ebawismarchsennino.eventbrite.com
$5/members  $10/nonmembers  to be collected at door

Scientists and Science Enthusiasts, Men and Women,  Members and Non-members Welcome!

****Thank you to E & K Scientific for In-kind Support of this Event****

 Uncategorized

NCC – hosted by eBAWIS – Winter Workshop

Jan 202012
 

February 4, 2012

Build Flexibility and Energy into your Career

Susan Bernstein, PhD, Work From Within

Future Proof Your Career: Building Flexibility to Navigate Changes

Learn how to navigate the future of work and create the calm, clarity, confidence and connection needed to thrive in the new economy. Prepare yourself for the inevitable changes in your professional career. Our world is changing quickly and familiar jobs are becoming obsolete. Now, instead of going to work, work often comes to us. The Millennial Generation grew up on technology, and is forcing us to use it more wisely and creatively. At the same time, we’re living in a time when the environment is increasingly polluted and resource-depleted. With all these changes, what do you need to know to make your career a success?

• The five major trends that will dictate your professional future
• Three conflicts that will have tremendous impact on your work — and your family/personal life
• Four key strategies you can adopt right now to be future-proof and flexible
• Techniques for creating calm, clarity, confidence and connection

Susan Bernstein, MBA, PhD is a consultant on the future of work, specializing in the human performance issues involved in major transitions. A veteran of management consulting, marketing, and executive development roles at companies like Intel, Accenture, and Franklin-Covey, Susan is keenly aware of the pressures in today’s workforce. As a strategist and an MBA, she is able to look into the future and see emerging trends. And with a PhD in the cutting-edge field of Somatic Psychology, she is able to help guide professionals through organizational transformation. She received her MBA at the University of California, Berkeley and her PhD from the Santa Barbara Graduate Institute.

Dr. JoAnn Dahlkoetter, PhD, Peak Performance Plan

“OLYMPIC THINKING” Strategies for High Energy, Productivity, and Balance 

This program, “Your Performing Edge “will give you a complete system with mindset tools and results-driven solutions to increase your energy, drive productivity, and enhance your performance under pressure. You will walk away with a powerful experience along with tools and resources for managing daily demands and strengthening your mind and body to be more resilient, to perform well, and to create inner balance under the most highly demanding work conditions. Learn leadership skills you can apply immediately:

• Your Gold Medal Mindset for Success – Olympic Thinking Tools
• Your Performing Edge – 3 P’s: Positive images, Power words, Present focus
• How to Build a Healthy, Balanced Lifestyle Professionally and Personally
• Visualize to Energize:  Confidence and Focus to Break through Barriers to Success

Dr. JoAnn Dahlkoetter is a world renowned performance coach to OLYMPIC Gold Medalists and CEOs, a sports psychologist, President of Performing Edge Coaching International, and author of 17 books including the national bestseller “Your Performing Edge.” Dr. JoAnn is an in-demand Stanford Olympic Keynote Speaker, winner of the San Francisco Marathon and 2nd woman in the World Championship Hawaii Ironman Triathlon. Her clients and audiences include Fortune 500 top executives and multi-national corporations, NASA scientists, surgeons, coaches and professional athletes. Dr. JoAnn is a frequent TV expert commentator on ABC, NBC, BBC, and Fox News.  In addition, Dr. JoAnn provides performance psychology consulting, customized corporate training and coach certification programs to reach your highest potential in business, sports, fitness and life.

Saturday, February 4, 2012, 9:00am- 2:00pm

***Please dress comfortably to participate in Dr. Susan Bernstein’s Tai Chi exercises***

Fee: $45 members, $55 non-members through 1.31.2012, $60 after 1.31.2012 and at the door.

Registration fee includes breakfast and lunch  

***INCLUDED FOR FIRST 70 TO REGISTER ARE COMPLEMENTARY COPIES OF DR. JOANN DAHLKOETTER’S BESTSELLER YOUR PERFORMING EDGE  ***

**REGISTER HERE**

Location: Bio-Rad, 225 Linus Pauling, Suite D, Hercules, CA 94547

Parking is in front of the Building

***Click Here for DIRECTIONS***

Non-scientists and men are welcome!

ebAWIS is a nonprofit organization and fees are collected only to cover our expenses

 

 Uncategorized

EbAWIS Chapter Meeting January 2012 – Networking

Dec 132011
 

East Bay Association for Women In Science Presents Our most anticipated event:

An Evening of Networking

­An entire Chapter meeting devoted to networking!  Our venue will guide you through a review of networking strategies; then, effective networking games that introduce you to many people will offer you the opportunity to:

  • Meet scientists as well as professionals interested in an affiliated career if you are job searching
  • Enhance your contacts if you are established in your present position
  • Polish presentation skills before the interview
  • Gather invaluable feedback about yourself in a friendly, fun, and informal environment

Light Dinner and Networking at 6:30 pm

Structured Program at 7:00 pm

Thursday, January 26, 2012

NOTE: Registering w/ Eventbrite will say free; however, fee will be collected at the door

Fee: $5 for members, $10 for non-members.

**REGISTER HERE**

Location: Novartis, 5400 Hollis St, Building X-310 Emeryville, CA

Parking is in front of the Building

***Click Here for DIRECTIONS***

ebAWIS is a nonprofit organization and the fee covers cost of food

Scientists and Science Enthusiasts, Men and Women are Welcome!

Meetings are open to non-AWIS members

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